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Detection and quantification of the vacuolar H(+)ATPase using the Legionella effector protein SidK

Acidification of secretory and endocytic organelles is required for proper receptor recycling, membrane traffic, protein degradation, and solute transport. Proton-pumping vacuolar H(+) ATPases (V-ATPases) are responsible for this luminal acidification, which increases progressively as secretory and...

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Detalles Bibliográficos
Autores principales: Maxson, Michelle E., Abbas, Yazan M., Wu, Jing Ze, Plumb, Jonathan D., Grinstein, Sergio, Rubinstein, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763849/
https://www.ncbi.nlm.nih.gov/pubmed/35024770
http://dx.doi.org/10.1083/jcb.202107174