Cruzipain Sulfotopes-Specific Antibodies Generate Cardiac Tissue Abnormalities and Favor Trypanosoma cruzi Infection in the BALB/c Mice Model of Experimental Chagas Disease

Trypanosoma cruzi cruzipain (Cz) bears a C-terminal domain (C-T) that contains sulfated epitopes “sulfotopes” (GlcNAc6S) on its unique N-glycosylation site. The effects of in vivo exposure to GlcNAc6S on heart tissue ultrastructure, immune responses, and along the outcome of infection by T. cruzi, w...

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Detalles Bibliográficos
Autores principales: Soprano, Luciana L., Ferrero, Maximiliano R., Landoni, Malena, García, Gabriela A., Esteva, Mónica I., Couto, Alicia S., Duschak, Vilma G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763857/
https://www.ncbi.nlm.nih.gov/pubmed/35059328
http://dx.doi.org/10.3389/fcimb.2021.814276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763857/
https://www.ncbi.nlm.nih.gov/pubmed/35059328
http://dx.doi.org/10.3389/fcimb.2021.814276

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