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The transcription factor HIF-1α mediates plasticity of NKp46(+) innate lymphoid cells in the gut

Gut innate lymphoid cells (ILCs) show remarkable phenotypic diversity, yet microenvironmental factors that drive this plasticity are incompletely understood. The balance between NKp46(+), IL-22–producing, group 3 ILCs (ILC3s) and interferon (IFN)-γ–producing group 1 ILCs (ILC1s) contributes to gut h...

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Detalles Bibliográficos
Autores principales: Krzywinska, Ewelina, Sobecki, Michal, Nagarajan, Shunmugam, Zacharjasz, Julian, Tambuwala, Murtaza M., Pelletier, Abigaelle, Cummins, Eoin, Gotthardt, Dagmar, Fandrey, Joachim, Kerdiles, Yann M., Peyssonnaux, Carole, Taylor, Cormac T., Sexl, Veronika, Stockmann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763886/
https://www.ncbi.nlm.nih.gov/pubmed/35024767
http://dx.doi.org/10.1084/jem.20210909