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gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes

Growth of long bones and vertebrae is maintained postnatally by a long-lasting pool of progenitor cells. Little is known about the molecular mechanisms that regulate the output and maintenance of the cells that give rise to mature cartilage. Here we demonstrate that postnatal chondrocyte-specific de...

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Detalles Bibliográficos
Autores principales: Liu, Nancy Q., Lin, Yucheng, Li, Liangliang, Lu, Jinxiu, Geng, Dawei, Zhang, Jiankang, Jashashvili, Tea, Buser, Zorica, Magallanes, Jenny, Tassey, Jade, Shkhyan, Ruzanna, Sarkar, Arijita, Lopez, Noah, Lee, Siyoung, Lee, Youngjoo, Wang, Liming, Petrigliano, Frank A., Van Handel, Ben, Lyons, Karen, Evseenko, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763901/
https://www.ncbi.nlm.nih.gov/pubmed/35039652
http://dx.doi.org/10.1038/s42003-021-02944-y