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Microbiome differential abundance methods produce different results across 38 datasets

Identifying differentially abundant microbes is a common goal of microbiome studies. Multiple methods are used interchangeably for this purpose in the literature. Yet, there are few large-scale studies systematically exploring the appropriateness of using these tools interchangeably, and the scale a...

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Detalles Bibliográficos
Autores principales: Nearing, Jacob T., Douglas, Gavin M., Hayes, Molly G., MacDonald, Jocelyn, Desai, Dhwani K., Allward, Nicole, Jones, Casey M. A., Wright, Robyn J., Dhanani, Akhilesh S., Comeau, André M., Langille, Morgan G. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763921/
https://www.ncbi.nlm.nih.gov/pubmed/35039521
http://dx.doi.org/10.1038/s41467-022-28034-z