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Irgm1 regulates metabolism and function in T cell subsets

Immunity Related GTPases (IRG) are a family of proteins produced during infection that regulate membrane remodeling events in cells, particularly autophagy and mitophagy. The human IRGM gene has been strongly associated with Crohn’s disease and other inflammatory diseases through Genome-Wide Associa...

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Detalles Bibliográficos
Autores principales: Alwarawrah, Yazan, Danzaki, Keiko, Nichols, Amanda G., Fee, Brian E., Bock, Cheryl, Kucera, Gary, Hale, Laura P., Taylor, Gregory A., MacIver, Nancie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763923/
https://www.ncbi.nlm.nih.gov/pubmed/35039539
http://dx.doi.org/10.1038/s41598-021-04442-x