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Epigenetic aging of the demographically non-aging naked mole-rat

The naked mole-rat (NMR) is an exceptionally long-lived rodent that shows no increase of mortality with age, defining it as a demographically non-aging mammal. Here, we perform bisulfite sequencing of the blood of > 100 NMRs, assessing > 3 million common CpG sites. Unsupervised clustering base...

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Detalles Bibliográficos
Autores principales: Kerepesi, Csaba, Meer, Margarita V., Ablaeva, Julia, Amoroso, Vince G., Lee, Sang-Goo, Zhang, Bohan, Gerashchenko, Maxim V., Trapp, Alexandre, Yim, Sun Hee, Lu, Ake T., Levine, Morgan E., Seluanov, Andrei, Horvath, Steve, Park, Thomas J., Gorbunova, Vera, Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763950/
https://www.ncbi.nlm.nih.gov/pubmed/35039495
http://dx.doi.org/10.1038/s41467-022-27959-9