Cargando…
Epigenetic aging of the demographically non-aging naked mole-rat
The naked mole-rat (NMR) is an exceptionally long-lived rodent that shows no increase of mortality with age, defining it as a demographically non-aging mammal. Here, we perform bisulfite sequencing of the blood of > 100 NMRs, assessing > 3 million common CpG sites. Unsupervised clustering base...
Autores principales: | Kerepesi, Csaba, Meer, Margarita V., Ablaeva, Julia, Amoroso, Vince G., Lee, Sang-Goo, Zhang, Bohan, Gerashchenko, Maxim V., Trapp, Alexandre, Yim, Sun Hee, Lu, Ake T., Levine, Morgan E., Seluanov, Andrei, Horvath, Steve, Park, Thomas J., Gorbunova, Vera, Gladyshev, Vadim N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763950/ https://www.ncbi.nlm.nih.gov/pubmed/35039495 http://dx.doi.org/10.1038/s41467-022-27959-9 |
Ejemplares similares
-
EPIGENETIC AGING OF THE DEMOGRAPHICALLY NONAGING NAKED MOLE RAT
por: Kerepesi, Csaba
Publicado: (2022) -
Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties
por: Takasugi, Masaki, et al.
Publicado: (2020) -
Ectopic cervical thymi and no thymic involution until midlife in naked mole rats
por: Emmrich, Stephan, et al.
Publicado: (2021) -
Emerging rejuvenation strategies—Reducing the biological age
por: Zhang, Bohan, et al.
Publicado: (2021) -
Epigenetic clocks reveal a rejuvenation event during embryogenesis followed by aging
por: Kerepesi, Csaba, et al.
Publicado: (2021)