Single-molecule analysis of specificity and multivalency in binding of short linear substrate motifs to the APC/C

Robust regulatory signals in the cell often depend on interactions between short linear motifs (SLiMs) and globular proteins. Many of these interactions are poorly characterized because the binding proteins cannot be produced in the amounts needed for traditional methods. To address this problem, we...

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Detalles Bibliográficos
Autores principales: Hartooni, Nairi, Sung, Jongmin, Jain, Ankur, Morgan, David O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764033/
https://www.ncbi.nlm.nih.gov/pubmed/35039540
http://dx.doi.org/10.1038/s41467-022-28031-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764033/
https://www.ncbi.nlm.nih.gov/pubmed/35039540
http://dx.doi.org/10.1038/s41467-022-28031-2

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