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Single-molecule analysis of specificity and multivalency in binding of short linear substrate motifs to the APC/C
Robust regulatory signals in the cell often depend on interactions between short linear motifs (SLiMs) and globular proteins. Many of these interactions are poorly characterized because the binding proteins cannot be produced in the amounts needed for traditional methods. To address this problem, we...
Autores principales: | Hartooni, Nairi, Sung, Jongmin, Jain, Ankur, Morgan, David O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764033/ https://www.ncbi.nlm.nih.gov/pubmed/35039540 http://dx.doi.org/10.1038/s41467-022-28031-2 |
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