Transcriptomic analysis of choroidal neovascularization reveals dysregulation of immune and fibrosis pathways that are attenuated by a novel anti-fibrotic treatment

Neovascular AMD (nAMD) leads to vision loss and is a leading cause of visual impairment in the industrialised world. Current treatments that target blood vessel growth have not been able to treat subretinal fibrosis and nAMD patients continue to lose vision. The molecular mechanisms involved in the...

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Detalles Bibliográficos
Autores principales: Brandli, Alice, Khong, Fay L., Kong, Roy C. K., Kelly, Darren J., Fletcher, Erica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764037/
https://www.ncbi.nlm.nih.gov/pubmed/35039609
http://dx.doi.org/10.1038/s41598-022-04845-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764037/
https://www.ncbi.nlm.nih.gov/pubmed/35039609
http://dx.doi.org/10.1038/s41598-022-04845-4

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