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Transcriptomic analysis of choroidal neovascularization reveals dysregulation of immune and fibrosis pathways that are attenuated by a novel anti-fibrotic treatment
Neovascular AMD (nAMD) leads to vision loss and is a leading cause of visual impairment in the industrialised world. Current treatments that target blood vessel growth have not been able to treat subretinal fibrosis and nAMD patients continue to lose vision. The molecular mechanisms involved in the...
Autores principales: | Brandli, Alice, Khong, Fay L., Kong, Roy C. K., Kelly, Darren J., Fletcher, Erica L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764037/ https://www.ncbi.nlm.nih.gov/pubmed/35039609 http://dx.doi.org/10.1038/s41598-022-04845-4 |
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