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Idebenone improves motor dysfunction, learning and memory by regulating mitophagy in MPTP-treated mice

The progression of Parkinson’s disease (PD) is often accompanied by the loss of substantia nigra dopaminergic neurons, mitophagy damage, learning, and memory impairment. Idebenone is a therapeutic drug that targets the mitochondria of neurodegenerative diseases, but its role in Parkinson’s disease a...

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Detalles Bibliográficos
Autores principales: Yan, Junqiang, Sun, Wenjie, Shen, Mengmeng, Zhang, Yongjiang, Jiang, Menghan, Liu, Anran, Ma, Hongxia, Lai, Xiaoyi, Wu, Jiannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764058/
https://www.ncbi.nlm.nih.gov/pubmed/35039479
http://dx.doi.org/10.1038/s41420-022-00826-8