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Idebenone improves motor dysfunction, learning and memory by regulating mitophagy in MPTP-treated mice
The progression of Parkinson’s disease (PD) is often accompanied by the loss of substantia nigra dopaminergic neurons, mitophagy damage, learning, and memory impairment. Idebenone is a therapeutic drug that targets the mitochondria of neurodegenerative diseases, but its role in Parkinson’s disease a...
Autores principales: | Yan, Junqiang, Sun, Wenjie, Shen, Mengmeng, Zhang, Yongjiang, Jiang, Menghan, Liu, Anran, Ma, Hongxia, Lai, Xiaoyi, Wu, Jiannan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764058/ https://www.ncbi.nlm.nih.gov/pubmed/35039479 http://dx.doi.org/10.1038/s41420-022-00826-8 |
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