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Pre-configuring chromatin architecture with histone modifications guides hematopoietic stem cell formation in mouse embryos
The gene activity underlying cell differentiation is regulated by a diverse set of transcription factors (TFs), histone modifications, chromatin structures and more. Although definitive hematopoietic stem cells (HSCs) are known to emerge via endothelial-to-hematopoietic transition (EHT), how the mul...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764075/ https://www.ncbi.nlm.nih.gov/pubmed/35039499 http://dx.doi.org/10.1038/s41467-022-28018-z |