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Pre-configuring chromatin architecture with histone modifications guides hematopoietic stem cell formation in mouse embryos

The gene activity underlying cell differentiation is regulated by a diverse set of transcription factors (TFs), histone modifications, chromatin structures and more. Although definitive hematopoietic stem cells (HSCs) are known to emerge via endothelial-to-hematopoietic transition (EHT), how the mul...

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Detalles Bibliográficos
Autores principales: Li, Chen C., Zhang, Guangyu, Du, Junjie, Liu, Di, Li, Zongcheng, Ni, Yanli, Zhou, Jie, Li, Yunqiao, Hou, Siyuan, Zheng, Xiaona, Lan, Yu, Liu, Bing, He, Aibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764075/
https://www.ncbi.nlm.nih.gov/pubmed/35039499
http://dx.doi.org/10.1038/s41467-022-28018-z