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Pantothenate biosynthesis is critical for chronic infection by the neurotropic parasite Toxoplasma gondii

Coenzyme A (CoA) is an essential molecule acting in metabolism, post-translational modification, and regulation of gene expression. While all organisms synthesize CoA, many, including humans, are unable to produce its precursor, pantothenate. Intriguingly, like most plants, fungi and bacteria, paras...

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Detalles Bibliográficos
Autores principales: Lunghi, Matteo, Kloehn, Joachim, Krishnan, Aarti, Varesio, Emmanuel, Vadas, Oscar, Soldati-Favre, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764084/
https://www.ncbi.nlm.nih.gov/pubmed/35039477
http://dx.doi.org/10.1038/s41467-022-27996-4