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Neuronally-enriched exosomal microRNA-27b mediates acute effects of ibuprofen on reward-related brain activity in healthy adults: a randomized, placebo-controlled, double-blind trial

This double-blind, randomized, within-subjects design evaluated whether acute administration of an anti-inflammatory drug modulates neuron-specific, inflammation-modulating microRNAs linked to macroscopic changes in reward processing. Twenty healthy subjects (10 females, 10 males) underwent a functi...

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Detalles Bibliográficos
Autores principales: Burrows, Kaiping, Figueroa-Hall, Leandra K., Kuplicki, Rayus, Stewart, Jennifer L., Alarbi, Ahlam M., Ramesh, Rajagopal, Savitz, Jonathan B., Teague, T. Kent, Risbrough, Victoria B., Paulus, Martin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764091/
https://www.ncbi.nlm.nih.gov/pubmed/35039595
http://dx.doi.org/10.1038/s41598-022-04875-y