Selective Deletion of the Mechanistic Target of Rapamycin From the Renal Collecting Duct Principal Cell in Mice Down-Regulates the Epithelial Sodium Channel

The mechanistic target of rapamycin (mTOR), a serine-threonine-specific kinase, is a cellular energy sensor, integrating growth factor and nutrient signaling. In the collecting duct (CD) of the kidney, the epithelial sodium channel (ENaC) essential in the determination of final urine Na+ losses, has...

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Detalles Bibliográficos
Autores principales: Chen, Bruce, Fluitt, Maurice B., Brown, Aaron L., Scott, Samantha, Gadicherla, Anirudh, Ecelbarger, Carolyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764147/
https://www.ncbi.nlm.nih.gov/pubmed/35058797
http://dx.doi.org/10.3389/fphys.2021.787521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764147/
https://www.ncbi.nlm.nih.gov/pubmed/35058797
http://dx.doi.org/10.3389/fphys.2021.787521

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