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San-Huang-Yi-Shen Capsule Ameliorates Diabetic Nephropathy in Rats Through Modulating the Gut Microbiota and Overall Metabolism

San-Huang-Yi-Shen capsule (SHYS) has been used in the treatment of diabetic nephropathy (DN) in clinic. However, the mechanisms of SHYS on DN remain unknown. In this study, we used a high-fat diet (HFD) combined with streptozotocin (STZ) injection to establish a DN rat model. Next, we used 16S rRNA...

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Detalles Bibliográficos
Autores principales: Su, Xiuhai, Yu, Wenxia, Liu, Airu, Wang, Congxiang, Li, Xiuzhen, Gao, Juanjuan, Liu, Xiaofei, Jiang, Wenhui, Yang, Yue, Lv, Shuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764181/
https://www.ncbi.nlm.nih.gov/pubmed/35058786
http://dx.doi.org/10.3389/fphar.2021.808867