Filamin A Is Required for NK Cell Cytotoxicity at the Expense of Cytokine Production via Synaptic Filamentous Actin Modulation

Natural killer (NK) cells are innate cytotoxic lymphocytes that efficiently eliminate malignant and virus-infected cells without prior activation via the directed and focused release of lytic granule contents for target cell lysis. This cytolytic process is tightly regulated at discrete checkpoint s...

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Detalles Bibliográficos
Autores principales: Kim, Nayoung, Yi, Eunbi, Kwon, Soon Jae, Park, Hyo Jin, Kwon, Hyung-Joon, Kim, Hun Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764188/
https://www.ncbi.nlm.nih.gov/pubmed/35058930
http://dx.doi.org/10.3389/fimmu.2021.792334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764188/
https://www.ncbi.nlm.nih.gov/pubmed/35058930
http://dx.doi.org/10.3389/fimmu.2021.792334

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