Multi-Omics Profiling Identifies Pathways Associated With CD8(+) T-Cell Activation in Severe Aplastic Anemia

Severe aplastic anemia (SAA) is an autoimmune disease characterized by immune-mediated destruction of hematopoietic stem and progenitor cells. Autoreactive CD8(+) T cells have been reported as the effector cells; however, the mechanisms regulating their cell activation in SAA remain largely unknown....

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Detalles Bibliográficos
Autores principales: You, Xing, Yang, Qiong, Yan, Kai, Wang, Song-Rong, Huang, Rong-Rong, Wang, Shun-Qing, Gao, Cai-Yue, Li, Liang, Lian, Zhe-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764265/
https://www.ncbi.nlm.nih.gov/pubmed/35058969
http://dx.doi.org/10.3389/fgene.2021.790990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764265/
https://www.ncbi.nlm.nih.gov/pubmed/35058969
http://dx.doi.org/10.3389/fgene.2021.790990

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