Cargando…

Self-Assembled Micellar Glutaminase Allosteric Inhibitor for Effective Therapeutic Intervention

INTRODUCTION: Kidney-type glutaminase (KGA) has been an important anti-tumor drug target, and KGA allosteric inhibitors attracted much interest for their superior enzymatic specificity with good drug safety profiles. For glutaminase allosteric inhibitors such as BPTES, CB-839 and Selen derivatives,...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Jinzhang, Chen, Zhao, Li, Jinxiu, Li, Di, Wang, Wenxi, Ruan, Benfang Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764296/
https://www.ncbi.nlm.nih.gov/pubmed/35058693
http://dx.doi.org/10.2147/IJN.S346596