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Self-Assembled Micellar Glutaminase Allosteric Inhibitor for Effective Therapeutic Intervention
INTRODUCTION: Kidney-type glutaminase (KGA) has been an important anti-tumor drug target, and KGA allosteric inhibitors attracted much interest for their superior enzymatic specificity with good drug safety profiles. For glutaminase allosteric inhibitors such as BPTES, CB-839 and Selen derivatives,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764296/ https://www.ncbi.nlm.nih.gov/pubmed/35058693 http://dx.doi.org/10.2147/IJN.S346596 |