Cargando…
SDHA Germline Variants in Adult Patients With SDHA-Mutant Gastrointestinal Stromal Tumor
BACKGROUND: SDH-deficient gastrointestinal stromal tumors (GIST) account for 20–40% of all KIT/PDGFRA-negative GIST and are due to mutations in one of the four SDH-complex subunits, with SDHA mutations as the most frequent. Here we sought to evaluate the presence and prevalence of SDHA variants in t...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764450/ https://www.ncbi.nlm.nih.gov/pubmed/35059314 http://dx.doi.org/10.3389/fonc.2021.778461 |