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SDHA Germline Variants in Adult Patients With SDHA-Mutant Gastrointestinal Stromal Tumor

BACKGROUND: SDH-deficient gastrointestinal stromal tumors (GIST) account for 20–40% of all KIT/PDGFRA-negative GIST and are due to mutations in one of the four SDH-complex subunits, with SDHA mutations as the most frequent. Here we sought to evaluate the presence and prevalence of SDHA variants in t...

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Detalles Bibliográficos
Autores principales:	Pantaleo, Maria A., Urbini, Milena, Schipani, Angela, Nannini, Margherita, Indio, Valentina, De Leo, Antonio, Vincenzi, Bruno, Brunello, Antonella, Grignani, Giovanni, Casagrande, Mariaelena, Fumagalli, Elena, Conca, Elena, Saponara, Maristella, Gruppioni, Elisa, Altimari, Annalisa, De Biase, Dario, Tallini, Giovanni, Ravegnini, Gloria, Turchetti, Daniela, Seri, Marco, Ardizzoni, Andrea, Secchiero, Paola, Astolfi, Annalisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764450/ https://www.ncbi.nlm.nih.gov/pubmed/35059314 http://dx.doi.org/10.3389/fonc.2021.778461

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