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Unmasking of CgYor1-Dependent Azole Resistance Mediated by Target of Rapamycin (TOR) and Calcineurin Signaling in Candida glabrata

In this study, 18 predicted membrane-localized ABC transporters of Candida glabrata were deleted individually to create a minilibrary of knockouts (KO). The transporter KOs were analyzed for their susceptibility toward antimycotic drugs. Although CgYOR1 has previously been reported to be upregulated...

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Detalles Bibliográficos
Autores principales: Kumari, Sonam, Kumar, Mohit, Esquivel, Brooke D., Wasi, Mohd, Pandey, Ajay Kumar, Kumar Khandelwal, Nitesh, Mondal, Alok K., White, Theodore C., Prasad, Rajendra, Gaur, Naseem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764518/
https://www.ncbi.nlm.nih.gov/pubmed/35038899
http://dx.doi.org/10.1128/mbio.03545-21