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Unmasking of CgYor1-Dependent Azole Resistance Mediated by Target of Rapamycin (TOR) and Calcineurin Signaling in Candida glabrata
In this study, 18 predicted membrane-localized ABC transporters of Candida glabrata were deleted individually to create a minilibrary of knockouts (KO). The transporter KOs were analyzed for their susceptibility toward antimycotic drugs. Although CgYOR1 has previously been reported to be upregulated...
Autores principales: | Kumari, Sonam, Kumar, Mohit, Esquivel, Brooke D., Wasi, Mohd, Pandey, Ajay Kumar, Kumar Khandelwal, Nitesh, Mondal, Alok K., White, Theodore C., Prasad, Rajendra, Gaur, Naseem A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764518/ https://www.ncbi.nlm.nih.gov/pubmed/35038899 http://dx.doi.org/10.1128/mbio.03545-21 |
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