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Enabling QTY Server for Designing Water-Soluble α-Helical Transmembrane Proteins

Membrane proteins, particularly those that are α-helical, such as transporters and G-protein-coupled receptors (GPCRs), have significant biological relevance. However, their expression and purification pose difficulties because of their poor water solubilities, which impedes progress in this field....

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Detalles Bibliográficos
Autores principales: Tao, Fei, Tang, Hongzhi, Zhang, Shuguang, Li, Mengke, Xu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764525/
https://www.ncbi.nlm.nih.gov/pubmed/35038913
http://dx.doi.org/10.1128/mbio.03604-21