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Pseudomonas aeruginosa C-Terminal Processing Protease CtpA Assembles into a Hexameric Structure That Requires Activation by a Spiral-Shaped Lipoprotein-Binding Partner

Pseudomonas aeruginosa CtpA is a carboxyl-terminal processing protease that partners with the outer membrane lipoprotein LbcA to degrade at least five cell wall-associated proteins, four of which are cell wall hydrolases. This activity plays an important role in supporting P. aeruginosa virulence in...

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Detalles Bibliográficos
Autores principales: Hsu, Hao-Chi, Wang, Michelle, Kovach, Amanda, Darwin, Andrew J., Li, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764530/
https://www.ncbi.nlm.nih.gov/pubmed/35038915
http://dx.doi.org/10.1128/mbio.03680-21