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Acyl-Coenzyme A Synthetase Long-Chain Family Member 4 Is Involved in Viral Replication Organelle Formation and Facilitates Virus Replication via Ferroptosis

Enterovirus infections can cause severe complications, such as poliomyelitis, encephalitis, myocarditis, meningitis, neurological pulmonary edema, and even death. Here, we used genome-wide CRISPR screens to gain new insight into the mechanism by which enteroviruses co-opt host pathways to potentiate...

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Detalles Bibliográficos
Autores principales: Kung, Yu-An, Chiang, Huan-Jung, Li, Mei-Ling, Gong, Yu-Nong, Chiu, Hsin-Ping, Hung, Chuan-Tien, Huang, Peng-Nien, Huang, Sheng-Yu, Wang, Pei-Yu, Hsu, Tsu-An, Brewer, Gary, Shih, Shin-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764547/
https://www.ncbi.nlm.nih.gov/pubmed/35038927
http://dx.doi.org/10.1128/mbio.02717-21