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lon Deletion Impairs Persister Cell Resuscitation in Escherichia coli

Bacterial persisters are nongrowing cells highly tolerant to bactericidal antibiotics. However, this tolerance is reversible and not mediated by heritable genetic changes. Lon, an ATP-dependent protease, has repeatedly been shown to play a critical role in fluoroquinolone persistence in Escherichia...

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Detalles Bibliográficos
Autores principales: Mohiuddin, Sayed Golam, Massahi, Aslan, Orman, Mehmet A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764555/
https://www.ncbi.nlm.nih.gov/pubmed/35038905
http://dx.doi.org/10.1128/mbio.02187-21