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A New Tool for the Analysis of the Effect of Intracerebrally Injected Anti-Amyloid-β Compounds

BACKGROUND: A wide range of techniques has been developed over the past decades to characterize amyloid-β (Aβ) pathology in mice. Until now, no method has been established to quantify spatial changes in Aβ plaque deposition due to targeted delivery of substances using ALZET(®) pumps. OBJECTIVE: Deve...

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Detalles Bibliográficos
Autores principales: Upīte, Jolanta, Brüning, Thomas, Möhle, Luisa, Brackhan, Mirjam, Bascuñana, Pablo, Jansone, Baiba, Pahnke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764605/
https://www.ncbi.nlm.nih.gov/pubmed/34719500
http://dx.doi.org/10.3233/JAD-215180