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Molecular Investigation of the Unfolded Protein Response in Select Human Tauopathies

BACKGROUND: Tauopathies are a group of neurodegenerative diseases associated with the accumulation of misfolded tau protein. The mechanisms underpinning tau-dependent proteinopathy remain to be elucidated. A protein quality control pathway within the endoplasmic reticulum, the unfolded protein respo...

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Detalles Bibliográficos
Autores principales: Pitera, Aleksandra P., Hartnell, Iain J., Scullard, Lucy, Williamson, Kirsten L., Boche, Delphine, O’Connor, Vincent, Deinhardt, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764631/
https://www.ncbi.nlm.nih.gov/pubmed/35088035
http://dx.doi.org/10.3233/ADR-210050