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Perspectives on the Role of APOE4 as a Therapeutic Target for Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disease that is coupled with chronic cognitive dysfunction. AD cases are mostly late onset, and genetic risk factors like the Apolipoprotein E (APOE) play a key role in this process. APOE ɛ2, APOE ɛ3, and APOE ɛ4 are three key alleles in the human APOE...

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Detalles Bibliográficos
Autores principales: Patel, Kavita, Srivastava, Siwangi, Kushwah, Shikha, Mani, Ashutosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764632/
https://www.ncbi.nlm.nih.gov/pubmed/35088039
http://dx.doi.org/10.3233/ADR-210027