Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol

Low-density lipoprotein (LDL) delivers cholesterol to mammalian cells through receptor-mediated endocytosis. The LDL cholesterol is liberated in lysosomes and transported to the plasma membrane (PM) and from there to the endoplasmic reticulum (ER). Excess ER cholesterol is esterified with a fatty ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Trinh, Michael N., Brown, Michael S., Seemann, Joachim, Vale, Gonçalo, McDonald, Jeffrey G., Goldstein, Joseph L., Lu, Feiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764668/
https://www.ncbi.nlm.nih.gov/pubmed/34992143
http://dx.doi.org/10.1073/pnas.2120411119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764668/
https://www.ncbi.nlm.nih.gov/pubmed/34992143
http://dx.doi.org/10.1073/pnas.2120411119

Ejemplares similares