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Lipoprotein-associated phospholipase A(2): A paradigm for allosteric regulation by membranes
Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) associates with low- and high-density lipoproteins in human plasma and specifically hydrolyzes circulating oxidized phospholipids involved in oxidative stress. The association of this enzyme with the lipoprotein’s phospholipid monolayer to access...
Autores principales: | Mouchlis, Varnavas D., Hayashi, Daiki, Vasquez, Alexis M., Cao, Jian, McCammon, J. Andrew, Dennis, Edward A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764669/ https://www.ncbi.nlm.nih.gov/pubmed/34996868 http://dx.doi.org/10.1073/pnas.2102953118 |
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