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Using machine learning to detect the differential usage of novel gene isoforms

BACKGROUND: Differential isoform usage is an important driver of inter-individual phenotypic diversity and is linked to various diseases and traits. However, accurately detecting the differential usage of different gene transcripts between groups can be difficult, in particular in less well annotate...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaopu, Hassan, Musa A., Prendergast, James G. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764765/
https://www.ncbi.nlm.nih.gov/pubmed/35042461
http://dx.doi.org/10.1186/s12859-022-04576-3