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Comparison and evaluation of statistical error models for scRNA-seq

BACKGROUND: Heterogeneity in single-cell RNA-seq (scRNA-seq) data is driven by multiple sources, including biological variation in cellular state as well as technical variation introduced during experimental processing. Deconvolving these effects is a key challenge for preprocessing workflows. Recen...

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Detalles Bibliográficos
Autores principales: Choudhary, Saket, Satija, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764781/
https://www.ncbi.nlm.nih.gov/pubmed/35042561
http://dx.doi.org/10.1186/s13059-021-02584-9