CircMET promotes tumor proliferation by enhancing CDKN2A mRNA decay and upregulating SMAD3

BACKGROUND: Functions of CircMET (hsa_circ_0082002) which is a circular RNA and derived from MET gene remain understood incompletely. In the present study, Xp11.2 translocation/NONO-TFE3 fusion renal cell carcinoma (NONO-TFE3 tRCC) with up-regulated CircMET was employed to investigate its mechanism...

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Detalles Bibliográficos
Autores principales: Yang, Lei, Chen, Yi, Liu, Ning, Lu, Yanwen, Ma, Wenliang, Yang, Zhenhao, Gan, Weidong, Li, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764797/
https://www.ncbi.nlm.nih.gov/pubmed/35042525
http://dx.doi.org/10.1186/s12943-022-01497-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764797/
https://www.ncbi.nlm.nih.gov/pubmed/35042525
http://dx.doi.org/10.1186/s12943-022-01497-w

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