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Resolving the difference between left-sided and right-sided colorectal cancer by single-cell sequencing

Colorectal cancers (CRCs) exhibit differences in incidence, pathogenesis, molecular pathways, and outcome depending on the location of the tumor. The transcriptomes of 27,927 single human CRC cells from 3 left-sided and 3 right-sided CRC patients were profiled by single-cell RNA-Seq (scRNA-Seq). Rig...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Zhang, Cuiyu, Wang, Xia, Dou, Dandan, Chen, Dawei, Li, Jingxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765049/
https://www.ncbi.nlm.nih.gov/pubmed/34793335
http://dx.doi.org/10.1172/jci.insight.152616