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Angiotensin-(1-7)/MasR axis promotes migration of monocytes/macrophages with a regulatory phenotype to perform phagocytosis and efferocytosis

Nonphlogistic migration of macrophages contributes to the clearance of pathogens and apoptotic cells, a critical step for the resolution of inflammation and return to homeostasis. Angiotensin-(1-7) [Ang-(1-7)] is a heptapeptide of the renin-angiotensin system that acts through Mas receptor (MasR). A...

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Detalles Bibliográficos
Autores principales: Zaidan, Isabella, Tavares, Luciana P., Sugimoto, Michelle A., Lima, Kátia M., Negreiros-Lima, Graziele L., Teixeira, Lívia C.R., Miranda, Thais C., Valiate, Bruno V.S., Cramer, Allysson, Vago, Juliana Priscila, Campolina-Silva, Gabriel H., Souza, Jéssica A.M., Grossi, Laís C., Pinho, Vanessa, Campagnole-Santos, Maria Jose, Santos, Robson A.S., Teixeira, Mauro M., Galvão, Izabela, Sousa, Lirlândia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765051/
https://www.ncbi.nlm.nih.gov/pubmed/34874920
http://dx.doi.org/10.1172/jci.insight.147819