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Atypical response to bacterial coinfection and persistent neutrophilic bronchoalveolar inflammation distinguish critical COVID-19 from influenza

Neutrophils are recognized as important circulating effector cells in the pathophysiology of severe coronavirus disease 2019 (COVID-19). However, their role within the inflamed lungs is incompletely understood. Here, we collected bronchoalveolar lavage (BAL) fluids and parallel blood samples of crit...

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Detalles Bibliográficos
Autores principales: Cambier, Seppe, Metzemaekers, Mieke, de Carvalho, Ana Carolina, Nooyens, Amber, Jacobs, Cato, Vanderbeke, Lore, Malengier-Devlies, Bert, Gouwy, Mieke, Heylen, Elisabeth, Meersseman, Philippe, Hermans, Greet, Wauters, Els, Wilmer, Alexander, Schols, Dominique, Matthys, Patrick, Opdenakker, Ghislain, Marques, Rafael Elias, Wauters, Joost, Vandooren, Jennifer, Proost, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765057/
https://www.ncbi.nlm.nih.gov/pubmed/34793331
http://dx.doi.org/10.1172/jci.insight.155055