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Mitochondrial membrane potential-enriched CHO host: a novel and powerful tool for improving biomanufacturing capability

With the aim of increasing protein productivity of Chinese hamster ovary (CHO) cells, we sought to generate new CHO hosts with favorable biomanufacturing phenotypes and improved functionality. Here, we present an innovative approach of enriching the CHO host cells with a high mitochondrial membrane...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Lina, Chaerkady, Raghothama, Wang, Junmin, Weng, Shao Huan Samuel, Wang, Chunlei, Qian, Chen, Cazares, Lisa, Hess, Sonja, Amaya, Peter, Zhu, Jie, Hatton, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765075/
https://www.ncbi.nlm.nih.gov/pubmed/35030984
http://dx.doi.org/10.1080/19420862.2021.2020081