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Comparative Analysis of Plasmodium falciparum Genotyping via SNP Detection, Microsatellite Profiling, and Whole-Genome Sequencing

Research efforts to combat antimalarial drug resistance rely on quick, robust, and sensitive methods to genetically characterize Plasmodium falciparum parasites. We developed a single-nucleotide polymorphism (SNP)-based genotyping method that can assess 33 drug resistance-conferring SNPs in dhfr, dh...

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Detalles Bibliográficos
Autores principales: Kanai, Mariko, Yeo, Tomas, Asua, Victor, Rosenthal, Philip J., Fidock, David A., Mok, Sachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765236/
https://www.ncbi.nlm.nih.gov/pubmed/34694871
http://dx.doi.org/10.1128/AAC.01163-21