Cargando…

Comparative Analysis of Plasmodium falciparum Genotyping via SNP Detection, Microsatellite Profiling, and Whole-Genome Sequencing

Research efforts to combat antimalarial drug resistance rely on quick, robust, and sensitive methods to genetically characterize Plasmodium falciparum parasites. We developed a single-nucleotide polymorphism (SNP)-based genotyping method that can assess 33 drug resistance-conferring SNPs in dhfr, dh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kanai, Mariko, Yeo, Tomas, Asua, Victor, Rosenthal, Philip J., Fidock, David A., Mok, Sachel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Mechanisms of Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765236/ https://www.ncbi.nlm.nih.gov/pubmed/34694871 http://dx.doi.org/10.1128/AAC.01163-21

Ejemplares similares

The Mu Subunit of Plasmodium falciparum Clathrin-Associated Adaptor Protein 2 Modulates In Vitro Parasite Response to Artemisinin and Quinine
por: Henriques, Gisela, et al.
Publicado: (2015)

Amplicon Deep Sequencing Reveals Multiple Genetic Events Lead to Treatment Failure with Atovaquone-Proguanil in Plasmodium falciparum
por: Castañeda-Mogollón, Daniel, et al.
Publicado: (2023)

Plasmodium falciparum GCN5 plays a key role in regulating artemisinin resistance-related stress responses
por: Lucky, Amuza Byaruhanga, et al.
Publicado: (2023)

The MSPDBL2 Codon 591 Polymorphism Is Associated with Lumefantrine In Vitro Drug Responses in Plasmodium falciparum Isolates from Kilifi, Kenya
por: Ochola-Oyier, Lynette Isabella, et al.
Publicado: (2015)

Reconciling the Potentially Irreconcilable? Genotypic and Phenotypic Amoxicillin-Clavulanate Resistance in Escherichia coli
por: Davies, Timothy J., et al.
Publicado: (2020)

Expression of Plasmodium vivax crt-o Is Related to Parasite Stage but Not Ex Vivo Chloroquine Susceptibility
por: Pava, Zuleima, et al.
Publicado: (2015)

Limited Polymorphism of the Kelch Propeller Domain in Plasmodium malariae and P. ovale Isolates from Thailand
por: Nakeesathit, Supatchara, et al.
Publicado: (2016)

Experimentally Engineered Mutations in a Ubiquitin Hydrolase, UBP-1, Modulate In Vivo Susceptibility to Artemisinin and Chloroquine in Plasmodium berghei
por: Simwela, Nelson V., et al.
Publicado: (2020)

How To Optimally Combine Genotypic and Phenotypic Drug Susceptibility Testing Methods for Pyrazinamide
por: Köser, Claudio U., et al.
Publicado: (2020)

Whole-Genome Sequencing for Drug Resistance Profile Prediction in Mycobacterium tuberculosis
por: Gygli, Sebastian M., et al.
Publicado: (2019)

Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae at a Single Institution: Insights into Endemicity from Whole-Genome Sequencing
por: Mathers, Amy J., et al.
Publicado: (2015)

Some Synonymous and Nonsynonymous gyrA Mutations in Mycobacterium tuberculosis Lead to Systematic False-Positive Fluoroquinolone Resistance Results with the Hain GenoType MTBDRsl Assays
por: Ajileye, Adebisi, et al.
Publicado: (2017)

Whole-Transcriptome and -Genome Analysis of Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolates Identifies Downregulation of ethA as a Mechanism of Ethionamide Resistance
por: de Welzen, Lynne, et al.
Publicado: (2017)

Identification of EnvC and Its Cognate Amidases as Novel Determinants of Intrinsic Resistance to Cationic Antimicrobial Peptides
por: Oguri, Tamiko, et al.
Publicado: (2016)

Low Level of Antifungal Resistance in Iranian Isolates of Candida glabrata Recovered from Blood Samples in a Multicenter Study from 2015 to 2018 and Potential Prognostic Values of Genotyping and Sequencing of PDR1
por: Arastehfar, Amir, et al.
Publicado: (2019)

Molecular Basis of Class A β-Lactamase Inhibition by Relebactam
por: Tooke, Catherine L., et al.
Publicado: (2019)

Imidazopyridine Compounds Inhibit Mycobacterial Growth by Depleting ATP Levels
por: O'Malley, Theresa, et al.
Publicado: (2018)

Boronic Acid Transition State Inhibitors as Potent Inactivators of KPC and CTX-M β-Lactamases: Biochemical and Structural Analyses
por: Alsenani, Tahani A., et al.
Publicado: (2023)

Cyclic AMP Effectors in African Trypanosomes Revealed by Genome-Scale RNA Interference Library Screening for Resistance to the Phosphodiesterase Inhibitor CpdA
por: Gould, Matthew K., et al.
Publicado: (2013)

Mutagenesis Mapping of the Protein-Protein Interaction Underlying FusB-Type Fusidic Acid Resistance
por: Cox, Georgina, et al.
Publicado: (2013)

A Novel Gene Amplification Causes Upregulation of the PatAB ABC Transporter and Fluoroquinolone Resistance in Streptococcus pneumoniae
por: Baylay, Alison J., et al.
Publicado: (2015)

Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles
por: Makena, Anne, et al.
Publicado: (2016)

β-Lactamase Characterization of Gram-Negative Pathogens Recovered from Patients Enrolled in the Phase 2 Trials for Ceftazidime-Avibactam: Clinical Efficacies Analyzed against Subsets of Molecularly Characterized Isolates
por: Mendes, Rodrigo E., et al.
Publicado: (2016)

Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates
por: Karah, Nabil, et al.
Publicado: (2016)

First Report of cfr-Carrying Plasmids in the Pandemic Sequence Type 22 Methicillin-Resistant Staphylococcus aureus Staphylococcal Cassette Chromosome mec Type IV Clone
por: Shore, Anna C., et al.
Publicado: (2016)

Rapid Emergence and Evolution of Staphylococcus aureus Clones Harboring fusC-Containing Staphylococcal Cassette Chromosome Elements
por: Baines, Sarah L., et al.
Publicado: (2016)

Potential of Tetracycline Resistance Proteins To Evolve Tigecycline Resistance
por: Linkevicius, Marius, et al.
Publicado: (2016)

Caspofungin Treatment of Aspergillus fumigatus Results in ChsG-Dependent Upregulation of Chitin Synthesis and the Formation of Chitin-Rich Microcolonies
por: Walker, Louise A., et al.
Publicado: (2015)

Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers
por: Brem, Jürgen, et al.
Publicado: (2015)

Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A β-Lactamase with a Monobactam Substrate
por: Vandavasi, Venu Gopal, et al.
Publicado: (2016)

Missense Mutations in the Unfoldase ClpC1 of the Caseinolytic Protease Complex Are Associated with Pyrazinamide Resistance in Mycobacterium tuberculosis
por: Yee, Michelle, et al.
Publicado: (2017)

Echinocandin Resistance in Candida Species Isolates from Liver Transplant Recipients
por: Prigent, Gwénolé, et al.
Publicado: (2017)

In Vitro Tolerance of Drug-Naive Staphylococcus aureus Strain FDA209P to Vancomycin
por: Singh, Madhuri, et al.
Publicado: (2017)

Wild-Type and Non-Wild-Type Mycobacterium tuberculosis MIC Distributions for the Novel Fluoroquinolone Antofloxacin Compared with Those for Ofloxacin, Levofloxacin, and Moxifloxacin
por: Yu, Xia, et al.
Publicado: (2016)

The Heterodimeric ABC Transporter EfrCD Mediates Multidrug Efflux in Enterococcus faecalis
por: Hürlimann, Lea M., et al.
Publicado: (2016)

Homologous Recombination within Large Chromosomal Regions Facilitates Acquisition of β-Lactam and Vancomycin Resistance in Enterococcus faecium
por: García-Solache, Mónica, et al.
Publicado: (2016)

Characterization of In Vitro Resistance Development to the Novel Echinocandin CD101 in Candida Species
por: Locke, Jeffrey B., et al.
Publicado: (2016)

Interaction of Avibactam with Class B Metallo-β-Lactamases
por: Abboud, Martine I., et al.
Publicado: (2016)

IMP-27, a Unique Metallo-β-Lactamase Identified in Geographically Distinct Isolates of Proteus mirabilis
por: Dixon, Nyssa, et al.
Publicado: (2016)

The Expression of Antibiotic Resistance Methyltransferase Correlates with mRNA Stability Independently of Ribosome Stalling
por: Dzyubak, Ekaterina, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_akos55vg2jd5i4n3o3l0kgq6st