Mutation in the Plasmodium falciparum BTB/POZ Domain of K13 Protein Confers Artemisinin Resistance

Partial artemisinin resistance, defined in patients as a delayed parasite clearance following artemisinin-based treatment, is conferred by non-synonymous mutations in the Kelch beta-propeller domain of the Plasmodium falciparum k13 (pfk13) gene. Here, we carried out in vitro selection over a 1-year...

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Detalles Bibliográficos
Autores principales: Paloque, Lucie, Coppée, Romain, Stokes, Barbara H., Gnädig, Nina F., Niaré, Karamoko, Augereau, Jean-Michel, Fidock, David A., Clain, Jérôme, Benoit-Vical, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Epidemiology and Surveillance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765297/
https://www.ncbi.nlm.nih.gov/pubmed/34606334
http://dx.doi.org/10.1128/AAC.01320-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765297/
https://www.ncbi.nlm.nih.gov/pubmed/34606334
http://dx.doi.org/10.1128/AAC.01320-21

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