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DectiSomes: Glycan Targeting of Liposomal Drugs Improves the Treatment of Disseminated Candidiasis

Candida albicans causes life-threatening disseminated candidiasis. Individuals at greatest risk have weakened immune systems. An outer cell wall, exopolysaccharide matrix, and biofilm rich in oligoglucans and oligomannans help Candida spp. evade host defenses. Even after antifungal treatment, the 1-...

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Detalles Bibliográficos
Autores principales: Ambati, Suresh, Pham, Tuyetnhu, Lewis, Zachary A., Lin, Xiaorong, Meagher, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765427/
https://www.ncbi.nlm.nih.gov/pubmed/34633846
http://dx.doi.org/10.1128/AAC.01467-21