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DectiSomes: Glycan Targeting of Liposomal Drugs Improves the Treatment of Disseminated Candidiasis
Candida albicans causes life-threatening disseminated candidiasis. Individuals at greatest risk have weakened immune systems. An outer cell wall, exopolysaccharide matrix, and biofilm rich in oligoglucans and oligomannans help Candida spp. evade host defenses. Even after antifungal treatment, the 1-...
Autores principales: | Ambati, Suresh, Pham, Tuyetnhu, Lewis, Zachary A., Lin, Xiaorong, Meagher, Richard B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765427/ https://www.ncbi.nlm.nih.gov/pubmed/34633846 http://dx.doi.org/10.1128/AAC.01467-21 |
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