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OperonSEQer: A set of machine-learning algorithms with threshold voting for detection of operon pairs using short-read RNA-sequencing data

Operon prediction in prokaryotes is critical not only for understanding the regulation of endogenous gene expression, but also for exogenous targeting of genes using newly developed tools such as CRISPR-based gene modulation. A number of methods have used transcriptomics data to predict operons, bas...

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Detalles Bibliográficos
Autores principales: Krishnakumar, Raga, Ruffing, Anne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765615/
https://www.ncbi.nlm.nih.gov/pubmed/34986143
http://dx.doi.org/10.1371/journal.pcbi.1009731