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Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results

OBJECTIVES: Platelet activation underpins thrombus formation in ischemic stroke. The active, dimeric form of platelet receptor glycoprotein (GP) VI plays key roles by binding platelet ligands collagen and fibrin, leading to platelet activation. We investigated whether patients presenting with stroke...

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Detalles Bibliográficos
Autores principales: Induruwa, Isuru, McKinney, Harriet, Kempster, Carly, Thomas, Patrick, Batista, Joana, Malcor, Jean-Daniel, Bonna, Arkadiusz, McGee, Joanne, Bumanlag-Amis, Elaine, Rehnstrom, Karola, Ashford, Sophie, Soejima, Kenji, Ouwehand, Willem, Farndale, Richard, Downes, Kate, Warburton, Elizabeth, Moroi, Masaaki, Jung, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765640/
https://www.ncbi.nlm.nih.gov/pubmed/35041713
http://dx.doi.org/10.1371/journal.pone.0262695