Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses

The pandemic spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiological agent of Coronavirus Disease 2019 (COVID-19), represents an ongoing international health crisis. A key symptom of SARS-CoV-2 infection is the onset of fever, with a hyperthermic temperature range of...

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Detalles Bibliográficos
Autores principales: Herder, Vanessa, Dee, Kieran, Wojtus, Joanna K., Epifano, Ilaria, Goldfarb, Daniel, Rozario, Christoforos, Gu, Quan, Da Silva Filipe, Ana, Nomikou, Kyriaki, Nichols, Jenna, Jarrett, Ruth F., Stevenson, Andrew, McFarlane, Steven, Stewart, Meredith E., Szemiel, Agnieszka M., Pinto, Rute M., Masdefiol Garriga, Andreu, Davis, Chris, Allan, Jay, Graham, Sheila V., Murcia, Pablo R., Boutell, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765667/
https://www.ncbi.nlm.nih.gov/pubmed/34932557
http://dx.doi.org/10.1371/journal.pbio.3001065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765667/
https://www.ncbi.nlm.nih.gov/pubmed/34932557
http://dx.doi.org/10.1371/journal.pbio.3001065

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